Lentiviral integration preferences in transgenic mice
نویسندگان
چکیده
منابع مشابه
Identification of the Transgenic Integration Site in Immunodeficient tgε26 Human CD3ε Transgenic Mice
A strain of human CD3ε transgenic mice, tgε26, exhibits severe immunodeficiency associated with early arrest of T cell development. Complete loss of T cells is observed in homozygous tgε26 mice, but not in heterozygotes, suggesting that genomic disruption due to transgenic integration may contribute to the arrest of T cell development. Here we report the identification of the transgenic integra...
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ژورنال
عنوان ژورنال: genesis
سال: 2008
ISSN: 1526-954X,1526-968X
DOI: 10.1002/dvg.20435